Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1780787..1781292 Replicon chromosome
Accession NZ_CP064005
Organism Xanthomonas translucens pv. translucens strain XtKm7

Toxin (Protein)


Gene name relE Uniprot ID A0A1C3TRG2
Locus tag ISN30_RS07760 Protein ID WP_003479798.1
Coordinates 1780787..1781044 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag ISN30_RS07765 Protein ID WP_003468816.1
Coordinates 1781041..1781292 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN30_RS07735 1777096..1778163 + 1068 WP_172837969.1 endolytic transglycosylase MltG -
ISN30_RS07740 1778160..1778828 + 669 WP_003479795.1 dTMP kinase -
ISN30_RS07745 1778825..1779802 + 978 WP_003479796.1 DNA polymerase III subunit delta' -
ISN30_RS07750 1779799..1780152 + 354 WP_003479797.1 PilZ domain-containing protein -
ISN30_RS07760 1780787..1781044 - 258 WP_003479798.1 Txe/YoeB family addiction module toxin Toxin
ISN30_RS07765 1781041..1781292 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ISN30_RS07770 1781401..1781945 + 545 Protein_1520 endonuclease -
ISN30_RS07775 1781942..1782664 - 723 WP_003479800.1 ArsR family transcriptional regulator -
ISN30_RS07780 1782786..1783229 + 444 WP_003479801.1 nuclear transport factor 2 family protein -
ISN30_RS07785 1783265..1783819 - 555 WP_003479802.1 hypothetical protein -
ISN30_RS07790 1784986..1786221 - 1236 WP_065899003.1 citrate synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.61 Da        Isoelectric Point: 9.7381

>T179962 WP_003479798.1 NZ_CP064005:c1781044-1780787 [Xanthomonas translucens pv. translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA

Download         Length: 258 bp

>T179962 NZ_CP084902:146935-147351 [Escherichia coli]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT179962 WP_003468816.1 NZ_CP064005:c1781292-1781041 [Xanthomonas translucens pv. translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT179962 NZ_CP084902:146708-146938 [Escherichia coli]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGGCCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C3TRG2

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References