Detailed information of TA system TA179960

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 143286..144852
• Replicon: chromosome
• Accession: NZ_CP064005
• Organism: Xanthomonas translucens pv. translucens strain XtKm7

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: ISN30_RS00520
• Protein ID: WP_003480647.1
• Coordinates: 143286..144542 (+)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: ISN30_RS00525
• Protein ID: WP_003480646.1
• Coordinates: 144556..144852 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ISN30_RS00510	140597..141538	-	942	WP_003465367.1	alpha-E domain-containing protein	-
ISN30_RS00515	141538..142986	-	1449	WP_003480648.1	circularly permuted type 2 ATP-grasp protein	-
ISN30_RS00520	143286..144542	+	1257	WP_003480647.1	zeta toxin family protein	Toxin
ISN30_RS00525	144556..144852	+	297	WP_003480646.1	hypothetical protein	Antitoxin
ISN30_RS00530	145025..145300	-	276	WP_128809232.1	hypothetical protein	-
ISN30_RS00535	145381..145734	-	354	WP_003480645.1	dihydroneopterin aldolase	-
ISN30_RS00540	145727..146875	-	1149	WP_058360827.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
ISN30_RS00545	146997..147212	+	216	WP_003465342.1	30S ribosomal protein S21	-
ISN30_RS00550	147492..147941	+	450	WP_003480639.1	GatB/YqeY domain-containing protein	-
ISN30_RS00555	148076..148990	+	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.67 Da
• Isoelectric Point: 6.6145

>T179960 WP_003480647.1 NZ_CP064005:143286-144542 [Xanthomonas translucens pv. translucens]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPQLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T179960 NZ_CP084902:c86682-86533 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11088.54 Da
• Isoelectric Point: 7.3576

>AT179960 WP_003480646.1 NZ_CP064005:144556-144852 [Xanthomonas translucens pv. translucens]
MTHLKGADALALHKKLKERNASLRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT179960 NZ_CP084902:86726-86787 [Escherichia coli]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT