179958

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3436292..3436677 Replicon chromosome
Accession NZ_CP064004
Organism Xanthomonas translucens pv. translucens strain XtKm8

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag ISN31_RS15140 Protein ID WP_003469322.1
Coordinates 3436292..3436426 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag ISN31_RS15145 Protein ID WP_003469323.1
Coordinates 3436525..3436677 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN31_RS15125 3432728..3433651 - 924 WP_003476575.1 MBL fold metallo-hydrolase -
ISN31_RS15130 3433721..3435121 - 1401 WP_003476576.1 tryptophan--tRNA ligase -
ISN31_RS15135 3435232..3436083 + 852 WP_058360589.1 hypothetical protein -
ISN31_RS15140 3436292..3436426 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
ISN31_RS15145 3436525..3436677 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
ISN31_RS15150 3436821..3437744 - 924 WP_058360588.1 arginase -
ISN31_RS15160 3438132..3438968 - 837 WP_161993387.1 SPOR domain-containing protein -
ISN31_RS15165 3438978..3439718 - 741 WP_004427869.1 type III pantothenate kinase -
ISN31_RS15170 3439715..3440734 - 1020 WP_081049008.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
ISN31_RS15175 3440839..3441120 + 282 WP_038231761.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T179958 WP_003469322.1 NZ_CP064004:c3436426-3436292 [Xanthomonas translucens pv. translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T179958 NZ_CP084900:c4388039-4387866 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT179958 WP_003469323.1 NZ_CP064004:c3436677-3436525 [Xanthomonas translucens pv. translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT179958 NZ_CP084900:c4388363-4388067 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References