179957

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2579985..2580490 Replicon chromosome
Accession NZ_CP064004
Organism Xanthomonas translucens pv. translucens strain XtKm8

Toxin (Protein)


Gene name relE Uniprot ID A0A1C3TRG2
Locus tag ISN31_RS11195 Protein ID WP_003479798.1
Coordinates 2580233..2580490 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag ISN31_RS11190 Protein ID WP_003468816.1
Coordinates 2579985..2580236 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN31_RS11165 2575056..2576291 + 1236 WP_065899003.1 citrate synthase family protein -
ISN31_RS11170 2577458..2578012 + 555 WP_003479802.1 hypothetical protein -
ISN31_RS11175 2578048..2578491 - 444 WP_003479801.1 nuclear transport factor 2 family protein -
ISN31_RS11180 2578613..2579335 + 723 WP_003479800.1 ArsR family transcriptional regulator -
ISN31_RS11185 2579332..2579876 - 545 Protein_2207 endonuclease -
ISN31_RS11190 2579985..2580236 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ISN31_RS11195 2580233..2580490 + 258 WP_003479798.1 Txe/YoeB family addiction module toxin Toxin
ISN31_RS11205 2581125..2581478 - 354 WP_003479797.1 PilZ domain-containing protein -
ISN31_RS11210 2581475..2582452 - 978 WP_058360630.1 DNA polymerase III subunit delta' -
ISN31_RS11215 2582449..2583117 - 669 WP_003479795.1 dTMP kinase -
ISN31_RS11220 2583114..2584181 - 1068 WP_172837969.1 endolytic transglycosylase MltG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.61 Da        Isoelectric Point: 9.7381

>T179957 WP_003479798.1 NZ_CP064004:2580233-2580490 [Xanthomonas translucens pv. translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA

Download         Length: 258 bp

>T179957 NZ_CP084900:c4286522-4286172 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT179957 WP_003468816.1 NZ_CP064004:2579985-2580236 [Xanthomonas translucens pv. translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT179957 NZ_CP084900:c4286767-4286516 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C3TRG2

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References