Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4445988..4446373 Replicon chromosome
Accession NZ_CP064003
Organism Xanthomonas translucens pv. translucens strain XtKm9

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag ISN32_RS19105 Protein ID WP_003469322.1
Coordinates 4446239..4446373 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag ISN32_RS19100 Protein ID WP_003469323.1
Coordinates 4445988..4446140 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN32_RS19070 4441545..4441826 - 282 WP_038231761.1 hypothetical protein -
ISN32_RS19075 4441931..4442950 + 1020 WP_081049008.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
ISN32_RS19080 4442947..4443687 + 741 WP_004427869.1 type III pantothenate kinase -
ISN32_RS19085 4443697..4444533 + 837 WP_161993387.1 SPOR domain-containing protein -
ISN32_RS19095 4444921..4445844 + 924 WP_058360588.1 arginase -
ISN32_RS19100 4445988..4446140 + 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
ISN32_RS19105 4446239..4446373 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
ISN32_RS19110 4446582..4447433 - 852 WP_060744655.1 hypothetical protein -
ISN32_RS19115 4447544..4448944 + 1401 WP_060744654.1 tryptophan--tRNA ligase -
ISN32_RS19120 4449000..4449923 + 924 WP_064521685.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T179956 WP_003469322.1 NZ_CP064003:4446239-4446373 [Xanthomonas translucens pv. translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T179956 NZ_CP084900:3845813-3846091 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTATTTGGGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT179956 WP_003469323.1 NZ_CP064003:4445988-4446140 [Xanthomonas translucens pv. translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT179956 NZ_CP084900:3845550-3845810 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAAGTCGCGCGTGAAAAGGCATTACCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATTAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References