Detailed information of TA system TA179955

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 3122885..3123390
• Replicon: chromosome
• Accession: NZ_CP064003
• Organism: Xanthomonas translucens pv. translucens strain XtKm9

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ISN32_RS13260
• Protein ID: WP_058195736.1
• Coordinates: 3123133..3123390 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: ISN32_RS13255
• Protein ID: WP_003468816.1
• Coordinates: 3122885..3123136 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ISN32_RS13225	3119565..3120361	+	797	WP_153476699.1	IS5 family transposase	-
ISN32_RS13230	3120336..3120518	-	183	WP_196480047.1	hypothetical protein	-
ISN32_RS13235	3120515..3120835	-	321	Protein_2609	type II toxin-antitoxin system RelE/ParE family toxin	-
ISN32_RS13240	3120957..3121400	-	444	WP_058360632.1	nuclear transport factor 2 family protein	-
ISN32_RS13245	3121524..3122246	+	723	WP_058360631.1	ArsR family transcriptional regulator	-
ISN32_RS13250	3122243..3122776	-	534	Protein_2612	endonuclease	-
ISN32_RS13255	3122885..3123136	+	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
ISN32_RS13260	3123133..3123390	+	258	WP_058195736.1	Txe/YoeB family addiction module toxin	Toxin
ISN32_RS13270	3123681..3124034	-	354	WP_003479797.1	PilZ domain-containing protein	-
ISN32_RS13275	3124031..3125008	-	978	WP_003479796.1	DNA polymerase III subunit delta'	-
ISN32_RS13280	3125005..3125673	-	669	WP_003479795.1	dTMP kinase	-
ISN32_RS13285	3125670..3126737	-	1068	WP_172837969.1	endolytic transglycosylase MltG	-
ISN32_RS13290	3126807..3128156	-	1350	WP_003479793.1	aminodeoxychorismate synthase component I	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	3119963..3120361	398

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10216.73 Da
• Isoelectric Point: 9.7381

>T179955 WP_058195736.1 NZ_CP064003:3123133-3123390 [Xanthomonas translucens pv. translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGMLLIAQV
RYHYV

Nucleotide

• Length: 258 bp

>T179955 NZ_CP084900:c3839751-3839353 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACAGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT179955 WP_003468816.1 NZ_CP064003:3122885-3123136 [Xanthomonas translucens pv. translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT179955 NZ_CP084900:c3840047-3839754 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATTACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGAGCT
GAAAAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9