Detailed information of TA system TA179953

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 46803..48369
• Replicon: chromosome
• Accession: NZ_CP064003
• Organism: Xanthomonas translucens pv. translucens strain XtKm9

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: ISN32_RS00205
• Protein ID: WP_003480647.1
• Coordinates: 47113..48369 (-)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: ISN32_RS00200
• Protein ID: WP_003480646.1
• Coordinates: 46803..47099 (-)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ISN32_RS00170	42665..43579	-	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-
ISN32_RS00175	43714..44163	-	450	WP_003480639.1	GatB/YqeY domain-containing protein	-
ISN32_RS00180	44443..44658	-	216	WP_003465342.1	30S ribosomal protein S21	-
ISN32_RS00185	44780..45928	+	1149	WP_058360827.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
ISN32_RS00190	45921..46274	+	354	WP_003480645.1	dihydroneopterin aldolase	-
ISN32_RS00195	46355..46630	+	276	WP_128809232.1	hypothetical protein	-
ISN32_RS00200	46803..47099	-	297	WP_003480646.1	hypothetical protein	Antitoxin
ISN32_RS00205	47113..48369	-	1257	WP_003480647.1	zeta toxin family protein	Toxin
ISN32_RS00210	48669..50117	+	1449	WP_003480648.1	circularly permuted type 2 ATP-grasp protein	-
ISN32_RS00215	50117..51058	+	942	WP_003465367.1	alpha-E domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.67 Da
• Isoelectric Point: 6.6145

>T179953 WP_003480647.1 NZ_CP064003:c48369-47113 [Xanthomonas translucens pv. translucens]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPQLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T179953 NZ_CP084900:3533805-3534023 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTTTGGAAATTTATTCGCTAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11088.54 Da
• Isoelectric Point: 7.3576

>AT179953 WP_003480646.1 NZ_CP064003:c47099-46803 [Xanthomonas translucens pv. translucens]
MTHLKGADALALHKKLKERNASLRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT179953 NZ_CP084900:3533405-3533779 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG