Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 786289..786674 Replicon chromosome
Accession NZ_CP064002
Organism Xanthomonas translucens pv. translucens strain XtKm33

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag ISN33_RS03275 Protein ID WP_003469322.1
Coordinates 786540..786674 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag ISN33_RS03270 Protein ID WP_003469323.1
Coordinates 786289..786441 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN33_RS03240 781864..782127 - 264 WP_038238001.1 hypothetical protein -
ISN33_RS03245 782232..783251 + 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
ISN33_RS03250 783248..783988 + 741 WP_047325439.1 type III pantothenate kinase -
ISN33_RS03255 783998..784816 + 819 WP_047325438.1 SPOR domain-containing protein -
ISN33_RS03265 785222..786144 + 923 Protein_640 arginase -
ISN33_RS03270 786289..786441 + 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
ISN33_RS03275 786540..786674 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
ISN33_RS03280 786884..787735 - 852 WP_058359131.1 hypothetical protein -
ISN33_RS03285 787846..789246 + 1401 WP_003469320.1 tryptophan--tRNA ligase -
ISN33_RS03290 789309..790232 + 924 WP_003469319.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T179951 WP_003469322.1 NZ_CP064002:786540-786674 [Xanthomonas translucens pv. translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T179951 NZ_CP084900:2686001-2686108 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT179951 WP_003469323.1 NZ_CP064002:786289-786441 [Xanthomonas translucens pv. translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT179951 NZ_CP084900:c2685954-2685888 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References