Detailed information of TA system TA179950

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4635533..4637099
• Replicon: chromosome
• Accession: NZ_CP064001
• Organism: Xanthomonas translucens pv. translucens strain XtKm34

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: ISN34_RS19925
• Protein ID: WP_206710848.1
• Coordinates: 4635533..4636789 (+)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: ISN34_RS19930
• Protein ID: WP_081088129.1
• Coordinates: 4636803..4637099 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ISN34_RS19915	4632844..4633785	-	942	WP_060748403.1	alpha-E domain-containing protein	-
ISN34_RS19920	4633785..4635233	-	1449	WP_206710847.1	circularly permuted type 2 ATP-grasp protein	-
ISN34_RS19925	4635533..4636789	+	1257	WP_206710848.1	zeta toxin family protein	Toxin
ISN34_RS19930	4636803..4637099	+	297	WP_081088129.1	hypothetical protein	Antitoxin
ISN34_RS19935	4637628..4637981	-	354	WP_003480645.1	dihydroneopterin aldolase	-
ISN34_RS19940	4637974..4639122	-	1149	WP_206710849.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
ISN34_RS19945	4639244..4639459	+	216	WP_003465342.1	30S ribosomal protein S21	-
ISN34_RS19950	4639739..4640188	+	450	WP_003480639.1	GatB/YqeY domain-containing protein	-
ISN34_RS19955	4640323..4641237	+	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.72 Da
• Isoelectric Point: 6.8402

>T179950 WP_206710848.1 NZ_CP064001:4635533-4636789 [Xanthomonas translucens pv. translucens]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPKLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T179950 NZ_CP084900:c2415626-2415450 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11072.54 Da
• Isoelectric Point: 7.3576

>AT179950 WP_081088129.1 NZ_CP064001:4636803-4637099 [Xanthomonas translucens pv. translucens]
MTHLKGADALALHKKLKERNAALRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT179950 NZ_CP084900:c2415404-2414988 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTGCCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA