Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 731813..732198 Replicon chromosome
Accession NZ_CP064001
Organism Xanthomonas translucens pv. translucens strain XtKm34

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag ISN34_RS03000 Protein ID WP_003469322.1
Coordinates 732064..732198 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag ISN34_RS02995 Protein ID WP_003469323.1
Coordinates 731813..731965 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN34_RS02965 727391..727672 - 282 WP_038231761.1 hypothetical protein -
ISN34_RS02970 727777..728796 + 1020 WP_081306848.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
ISN34_RS02975 728793..729533 + 741 WP_004427869.1 type III pantothenate kinase -
ISN34_RS02980 729543..730358 + 816 WP_172837977.1 SPOR domain-containing protein -
ISN34_RS02990 730746..731669 + 924 WP_003476579.1 arginase -
ISN34_RS02995 731813..731965 + 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
ISN34_RS03000 732064..732198 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
ISN34_RS03005 732407..733258 - 852 WP_003476578.1 hypothetical protein -
ISN34_RS03010 733369..734769 + 1401 WP_003476576.1 tryptophan--tRNA ligase -
ISN34_RS03015 734860..735783 + 924 WP_003476575.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T179948 WP_003469322.1 NZ_CP064001:732064-732198 [Xanthomonas translucens pv. translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T179948 NZ_CP084900:2012802-2012905 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT179948 WP_003469323.1 NZ_CP064001:731813-731965 [Xanthomonas translucens pv. translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT179948 NZ_CP084900:c2012943-2012672 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References