Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 575632..576137 Replicon chromosome
Accession NZ_CP063997
Organism Xanthomonas translucens pv. undulosa strain XtKm15

Toxin (Protein)


Gene name relE Uniprot ID A0A2S0NY60
Locus tag ISN36_RS02605 Protein ID WP_003468814.1
Coordinates 575632..575889 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag ISN36_RS02610 Protein ID WP_003468816.1
Coordinates 575886..576137 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN36_RS02575 570864..572213 + 1350 WP_206712101.1 aminodeoxychorismate synthase component I -
ISN36_RS02580 572283..573350 + 1068 WP_170873989.1 endolytic transglycosylase MltG -
ISN36_RS02585 573347..574015 + 669 WP_058358980.1 dTMP kinase -
ISN36_RS02590 574012..574989 + 978 WP_003468812.1 DNA polymerase III subunit delta' -
ISN36_RS02595 574986..575339 + 354 WP_003468813.1 PilZ domain-containing protein -
ISN36_RS02605 575632..575889 - 258 WP_003468814.1 Txe/YoeB family addiction module toxin Toxin
ISN36_RS02610 575886..576137 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ISN36_RS02615 576293..577057 + 765 WP_003468819.1 endonuclease -
ISN36_RS02620 577054..577776 - 723 WP_003468821.1 ArsR family transcriptional regulator -
ISN36_RS02625 577900..578349 + 450 WP_003468823.1 nuclear transport factor 2 family protein -
ISN36_RS02630 578518..579207 + 690 WP_196479346.1 hypothetical protein -
ISN36_RS02635 579375..579650 - 276 WP_003468826.1 hypothetical protein -
ISN36_RS02640 579985..580275 + 291 WP_003468827.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10173.68 Da        Isoelectric Point: 9.6587

>T179943 WP_003468814.1 NZ_CP063997:c575889-575632 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Download         Length: 258 bp

>T179943 NZ_CP084900:894018-894425 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT179943 WP_003468816.1 NZ_CP063997:c576137-575886 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT179943 NZ_CP084900:893771-894037 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S0NY60

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References