Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3902712..3903097 Replicon chromosome
Accession NZ_CP063996
Organism Xanthomonas translucens pv. undulosa strain XtFa1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag ISN37_RS17005 Protein ID WP_003469322.1
Coordinates 3902712..3902846 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag ISN37_RS17010 Protein ID WP_003469323.1
Coordinates 3902945..3903097 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN37_RS16990 3899144..3900067 - 924 WP_003469319.1 MBL fold metallo-hydrolase -
ISN37_RS16995 3900137..3901537 - 1401 WP_003469320.1 tryptophan--tRNA ligase -
ISN37_RS17000 3901648..3902502 + 855 WP_003469321.1 hypothetical protein -
ISN37_RS17005 3902712..3902846 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
ISN37_RS17010 3902945..3903097 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
ISN37_RS17015 3903242..3904164 - 923 Protein_3346 arginase -
ISN37_RS17025 3904570..3905388 - 819 WP_047325438.1 SPOR domain-containing protein -
ISN37_RS17030 3905398..3906138 - 741 WP_003469293.1 type III pantothenate kinase -
ISN37_RS17035 3906135..3907154 - 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
ISN37_RS17040 3907259..3907522 + 264 WP_038238001.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T179942 WP_003469322.1 NZ_CP063996:c3902846-3902712 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T179942 NZ_CP084900:750497-750793 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT179942 WP_003469323.1 NZ_CP063996:c3903097-3902945 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT179942 NZ_CP084900:750795-751190 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References