Detailed information of TA system TA179941

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 3179107..3179612
• Replicon: chromosome
• Accession: NZ_CP063996
• Organism: Xanthomonas translucens pv. undulosa strain XtFa1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A2S0NY60
• Locus tag: ISN37_RS13600
• Protein ID: WP_003468814.1
• Coordinates: 3179355..3179612 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: ISN37_RS13595
• Protein ID: WP_003468816.1
• Coordinates: 3179107..3179358 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ISN37_RS13565	3174969..3175259	-	291	WP_003468827.1	hypothetical protein	-
ISN37_RS13570	3175594..3175869	+	276	WP_003468826.1	hypothetical protein	-
ISN37_RS13575	3176037..3176726	-	690	WP_196479346.1	hypothetical protein	-
ISN37_RS13580	3176895..3177344	-	450	WP_003468823.1	nuclear transport factor 2 family protein	-
ISN37_RS13585	3177468..3178190	+	723	WP_003468821.1	ArsR family transcriptional regulator	-
ISN37_RS13590	3178187..3178951	-	765	WP_003468819.1	endonuclease	-
ISN37_RS13595	3179107..3179358	+	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
ISN37_RS13600	3179355..3179612	+	258	WP_003468814.1	Txe/YoeB family addiction module toxin	Toxin
ISN37_RS13610	3179905..3180258	-	354	WP_003468813.1	PilZ domain-containing protein	-
ISN37_RS13615	3180255..3181232	-	978	WP_003468812.1	DNA polymerase III subunit delta'	-
ISN37_RS13620	3181229..3181897	-	669	WP_003468811.1	dTMP kinase	-
ISN37_RS13625	3181894..3182961	-	1068	WP_170873989.1	endolytic transglycosylase MltG	-
ISN37_RS13630	3183031..3184380	-	1350	WP_003468809.1	aminodeoxychorismate synthase component I	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10173.68 Da
• Isoelectric Point: 9.6587

>T179941 WP_003468814.1 NZ_CP063996:3179355-3179612 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Nucleotide

• Length: 258 bp

>T179941 NZ_CP084900:686025-686339 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT179941 WP_003468816.1 NZ_CP063996:3179107-3179358 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT179941 NZ_CP084900:686336-686752 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Structures

Toxin

• AlphaFold DB: A0A2S0NY60

Antitoxin

• AlphaFold DB: A0A1C3TRJ9