Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 2196322..2196992 | Replicon | chromosome |
| Accession | NZ_CP063996 | ||
| Organism | Xanthomonas translucens pv. undulosa strain XtFa1 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | ISN37_RS09430 | Protein ID | WP_003473425.1 |
| Coordinates | 2196322..2196741 (-) | Length | 140 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A2S7EM03 |
| Locus tag | ISN37_RS09435 | Protein ID | WP_003473422.1 |
| Coordinates | 2196738..2196992 (-) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISN37_RS09390 | 2191544..2191912 | - | 369 | WP_003466572.1 | conjugal transfer transcriptional regulator TraJ | - |
| ISN37_RS09395 | 2191915..2192199 | - | 285 | WP_003466574.1 | hypothetical protein | - |
| ISN37_RS09400 | 2192211..2192453 | - | 243 | WP_003466577.1 | type I toxin-antitoxin system ptaRNA1 family toxin | - |
| ISN37_RS09405 | 2192567..2193967 | - | 1401 | WP_003466580.1 | P-type conjugative transfer protein TrbL | - |
| ISN37_RS09410 | 2193969..2194127 | - | 159 | WP_155522240.1 | hypothetical protein | - |
| ISN37_RS09415 | 2194138..2194842 | - | 705 | WP_003466583.1 | P-type conjugative transfer protein TrbJ | - |
| ISN37_RS09420 | 2194941..2195234 | + | 294 | WP_038237253.1 | transposase | - |
| ISN37_RS09425 | 2195231..2196091 | + | 861 | WP_060748765.1 | IS3 family transposase | - |
| ISN37_RS09430 | 2196322..2196741 | - | 420 | WP_003473425.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| ISN37_RS09435 | 2196738..2196992 | - | 255 | WP_003473422.1 | hypothetical protein | Antitoxin |
| ISN37_RS09440 | 2197404..2197685 | - | 282 | WP_003473419.1 | TraK family protein | - |
| ISN37_RS09445 | 2198271..2199373 | + | 1103 | Protein_1861 | IS3 family transposase | - |
| ISN37_RS09450 | 2199491..2199972 | + | 482 | Protein_1862 | IS3 family transposase | - |
| ISN37_RS09455 | 2200030..2200773 | + | 744 | Protein_1863 | IS3 family transposase | - |
| ISN37_RS09460 | 2200752..2201720 | - | 969 | WP_058197552.1 | IS5 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 2195864..2200556 | 4692 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 14944.21 Da Isoelectric Point: 5.2082
>T179940 WP_003473425.1 NZ_CP063996:c2196741-2196322 [Xanthomonas translucens pv. undulosa]
MIVLDTNVVSEAMKPEPNPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
MIVLDTNVVSEAMKPEPNPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
Download Length: 420 bp
>T179940 NZ_CP084900:c637962-637498 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGATGCTTTAGTTGC
CGAAGTCGAGGCATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGTAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGATGCTTTAGTTGC
CGAAGTCGAGGCATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGTAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9507.88 Da Isoelectric Point: 7.2071
>AT179940 WP_003473422.1 NZ_CP063996:c2196992-2196738 [Xanthomonas translucens pv. undulosa]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
Download Length: 255 bp
>AT179940 NZ_CP084900:c638297-637962 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCTGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCTGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|