179938

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2666006..2666391 Replicon chromosome
Accession NZ_CP063993
Organism Xanthomonas translucens pv. undulosa strain XtLr8

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag ISN38_RS11205 Protein ID WP_003469322.1
Coordinates 2666257..2666391 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag ISN38_RS11200 Protein ID WP_003469323.1
Coordinates 2666006..2666158 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN38_RS11170 2661581..2661844 - 264 WP_038238001.1 hypothetical protein -
ISN38_RS11175 2661949..2662968 + 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
ISN38_RS11180 2662965..2663705 + 741 WP_047325439.1 type III pantothenate kinase -
ISN38_RS11185 2663715..2664533 + 819 WP_047325438.1 SPOR domain-containing protein -
ISN38_RS11195 2664939..2665861 + 923 Protein_2187 arginase -
ISN38_RS11200 2666006..2666158 + 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
ISN38_RS11205 2666257..2666391 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
ISN38_RS11210 2666601..2667452 - 852 WP_206711803.1 hypothetical protein -
ISN38_RS11215 2667563..2668963 + 1401 WP_003469320.1 tryptophan--tRNA ligase -
ISN38_RS11220 2669026..2669949 + 924 WP_206711804.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T179938 WP_003469322.1 NZ_CP063993:2666257-2666391 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T179938 NZ_CP084899:c4590147-4589806 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCATGTCACCGTCGGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CTGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGAGGAGAGCGAA
CTGATGCAGTCGCTACGCCAGGTGTGCAAACTGTCGGCGCGTAAACAAAAGCAGGTGCAGGCGTTTATTGGAGTGATTGC
CGGTAAACAGAAAGTCGCGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT179938 WP_003469323.1 NZ_CP063993:2666006-2666158 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT179938 NZ_CP084899:4590142-4590218 [Escherichia coli]
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References