Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1381569..1382074 Replicon chromosome
Accession NZ_CP063993
Organism Xanthomonas translucens pv. undulosa strain XtLr8

Toxin (Protein)


Gene name relE Uniprot ID A0A2S0NY60
Locus tag ISN38_RS05655 Protein ID WP_003468814.1
Coordinates 1381817..1382074 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag ISN38_RS05650 Protein ID WP_003468816.1
Coordinates 1381569..1381820 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN38_RS05620 1377431..1377721 - 291 WP_003468827.1 hypothetical protein -
ISN38_RS05625 1378056..1378331 + 276 WP_003468826.1 hypothetical protein -
ISN38_RS05630 1378499..1379188 - 690 WP_196479346.1 hypothetical protein -
ISN38_RS05635 1379357..1379806 - 450 WP_003468823.1 nuclear transport factor 2 family protein -
ISN38_RS05640 1379930..1380652 + 723 WP_003468821.1 ArsR family transcriptional regulator -
ISN38_RS05645 1380649..1381413 - 765 WP_003468819.1 endonuclease -
ISN38_RS05650 1381569..1381820 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ISN38_RS05655 1381817..1382074 + 258 WP_003468814.1 Txe/YoeB family addiction module toxin Toxin
ISN38_RS05665 1382367..1382720 - 354 WP_003468813.1 PilZ domain-containing protein -
ISN38_RS05670 1382717..1383694 - 978 WP_003468812.1 DNA polymerase III subunit delta' -
ISN38_RS05675 1383691..1384359 - 669 WP_058358980.1 dTMP kinase -
ISN38_RS05680 1384356..1385423 - 1068 WP_170873989.1 endolytic transglycosylase MltG -
ISN38_RS05685 1385493..1386842 - 1350 WP_206712101.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10173.68 Da        Isoelectric Point: 9.6587

>T179937 WP_003468814.1 NZ_CP063993:1381817-1382074 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Download         Length: 258 bp

>T179937 NZ_CP084899:c4543583-4543326 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT179937 WP_003468816.1 NZ_CP063993:1381569-1381820 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT179937 NZ_CP084899:c4543314-4542769 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S0NY60

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References