Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4168417..4168562 Replicon chromosome
Accession NZ_CP063992
Organism Klebsiella pneumoniae strain M164-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4168424..4168526 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4168417..4168562 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HXS86_RS20400 4163948..4165381 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HXS86_RS20405 4165497..4165736 + 240 WP_002911393.1 YebV family protein -
HXS86_RS20410 4165834..4166025 + 192 WP_002911395.1 YebW family protein -
HXS86_RS20415 4166022..4166675 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
HXS86_RS20420 4166832..4167800 + 969 WP_014907334.1 VirK/YbjX family protein -
HXS86_RS20425 4167905..4168048 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 4168417..4168562 + 146 - - Antitoxin
- 4168424..4168526 - 103 - - Toxin
HXS86_RS20430 4168685..4169023 - 339 WP_002911404.1 YebY family protein -
HXS86_RS20435 4169040..4169909 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HXS86_RS20440 4169913..4170287 - 375 WP_039819395.1 CopC domain-containing protein YobA -
HXS86_RS20445 4170400..4170630 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HXS86_RS20450 4170709..4171368 + 660 WP_002911407.1 exodeoxyribonuclease X -
HXS86_RS20455 4171372..4173432 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179926 NZ_CP063992:c4168526-4168424 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179926 NZ_CP063992:4168417-4168562 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References