Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2220233..2220501 Replicon chromosome
Accession NZ_CP063983
Organism Escherichia coli strain 25DN

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2220361..2220463 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2220233..2220501 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IR210_RS10300 2216785..2217447 - 663 WP_000944256.1 exodeoxyribonuclease X -
IR210_RS10305 2217471..2218127 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
IR210_RS10310 2218230..2218460 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IR210_RS10315 2218599..2218973 + 375 WP_000168747.1 CopC domain-containing protein YobA -
IR210_RS10320 2218977..2219849 + 873 WP_194446354.1 copper homeostasis membrane protein CopD -
IR210_RS10325 2219862..2220203 + 342 WP_000984819.1 YebY family protein -
- 2220233..2220501 - 269 - - Antitoxin
- 2220361..2220463 + 103 - - Toxin
IR210_RS10330 2220598..2221254 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
IR210_RS10335 2221255..2221446 - 192 WP_001317886.1 YebW family protein -
IR210_RS10340 2221551..2221787 - 237 WP_001295499.1 DUF1480 family protein -
IR210_RS10345 2221905..2223344 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179894 NZ_CP063983:2220361-2220463 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT179894 NZ_CP063983:c2220501-2220233 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References