Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2962874..2963018 Replicon chromosome
Accession NZ_CP063954
Organism Klebsiella variicola strain S129-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2962880..2962982 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2962874..2963018 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD50_RS14220 2958397..2959830 + 1434 WP_194394513.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IOD50_RS14225 2959946..2960185 + 240 WP_002911393.1 YebV family protein -
IOD50_RS14230 2960283..2960474 + 192 WP_002911395.1 YebW family protein -
IOD50_RS14235 2960471..2961124 - 654 WP_008804273.1 protein-serine/threonine phosphatase -
IOD50_RS14240 2961280..2962248 + 969 WP_194394512.1 VirK/YbjX family protein -
IOD50_RS14245 2962352..2962495 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 2962874..2963018 + 145 - - Antitoxin
- 2962880..2962982 - 103 - - Toxin
IOD50_RS14250 2963140..2963478 - 339 WP_008804271.1 YebY family protein -
IOD50_RS14255 2963495..2964364 - 870 WP_194394511.1 copper homeostasis membrane protein CopD -
IOD50_RS14260 2964368..2964742 - 375 WP_008804269.1 CopC domain-containing protein YobA -
IOD50_RS14265 2964856..2965086 + 231 WP_012541260.1 DNA polymerase III subunit theta -
IOD50_RS14270 2965165..2965824 + 660 WP_008804267.1 exodeoxyribonuclease X -
IOD50_RS14275 2965828..2967888 - 2061 WP_012541258.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179831 NZ_CP063954:c2962982-2962880 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179831 NZ_CP063954:2962874-2963018 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References