Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3382134..3382278 Replicon chromosome
Accession NZ_CP063953
Organism Klebsiella variicola strain S131-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3382170..3382272 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3382134..3382278 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISD12_RS16005 3377264..3379324 + 2061 WP_012541258.1 oligopeptidase B -
ISD12_RS16010 3379328..3379987 - 660 WP_008804267.1 exodeoxyribonuclease X -
ISD12_RS16015 3380066..3380296 - 231 WP_012541260.1 DNA polymerase III subunit theta -
ISD12_RS16020 3380410..3380784 + 375 WP_008804269.1 CopC domain-containing protein YobA -
ISD12_RS16025 3380788..3381657 + 870 WP_194394511.1 copper homeostasis membrane protein CopD -
ISD12_RS16030 3381674..3382012 + 339 WP_008804271.1 YebY family protein -
- 3382134..3382278 - 145 - - Antitoxin
- 3382170..3382272 + 103 - - Toxin
ISD12_RS16035 3382657..3382800 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
ISD12_RS16040 3382904..3383872 - 969 WP_194394512.1 VirK/YbjX family protein -
ISD12_RS16045 3384028..3384681 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
ISD12_RS16050 3384678..3384869 - 192 WP_002911395.1 YebW family protein -
ISD12_RS16055 3384967..3385206 - 240 WP_002911393.1 YebV family protein -
ISD12_RS16060 3385322..3386755 - 1434 WP_194394513.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179819 NZ_CP063953:3382170-3382272 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179819 NZ_CP063953:c3382278-3382134 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References