Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 952400..952545 Replicon chromosome
Accession NZ_CP063945
Organism Klebsiella pneumoniae strain S166-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 952436..952538 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 952400..952545 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD25_RS04500 947530..949590 + 2061 WP_004151449.1 oligopeptidase B -
IOD25_RS04505 949594..950253 - 660 WP_002911407.1 exodeoxyribonuclease X -
IOD25_RS04510 950332..950562 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IOD25_RS04515 950675..951049 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IOD25_RS04520 951053..951922 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
IOD25_RS04525 951939..952277 + 339 WP_016529031.1 YebY family protein -
- 952400..952545 - 146 - - Antitoxin
- 952436..952538 + 103 - - Toxin
IOD25_RS04530 952913..953056 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IOD25_RS04535 953161..954129 - 969 WP_004151446.1 VirK/YbjX family protein -
IOD25_RS04540 954286..954939 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IOD25_RS04545 954936..955127 - 192 WP_002911395.1 YebW family protein -
IOD25_RS04550 955225..955464 - 240 WP_002911393.1 YebV family protein -
IOD25_RS04555 955580..957013 - 1434 WP_194433240.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179787 NZ_CP063945:952436-952538 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179787 NZ_CP063945:c952545-952400 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References