Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1443581..1443726 Replicon chromosome
Accession NZ_CP063943
Organism Klebsiella pneumoniae strain BS329-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1443617..1443719 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1443581..1443726 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA55_RS06915 1438711..1440771 + 2061 WP_004148850.1 oligopeptidase B -
ISA55_RS06920 1440775..1441434 - 660 WP_002911407.1 exodeoxyribonuclease X -
ISA55_RS06925 1441513..1441743 - 231 WP_025860700.1 DNA polymerase III subunit theta -
ISA55_RS06930 1441856..1442230 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ISA55_RS06935 1442234..1443103 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISA55_RS06940 1443120..1443458 + 339 WP_002911404.1 YebY family protein -
- 1443581..1443726 - 146 - - Antitoxin
- 1443617..1443719 + 103 - - Toxin
ISA55_RS06945 1444094..1444237 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ISA55_RS06950 1444342..1445310 - 969 WP_014907334.1 VirK/YbjX family protein -
ISA55_RS06955 1445467..1446120 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
ISA55_RS06960 1446117..1446308 - 192 WP_002911395.1 YebW family protein -
ISA55_RS06965 1446406..1446645 - 240 WP_002911393.1 YebV family protein -
ISA55_RS06970 1446761..1448194 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179769 NZ_CP063943:1443617-1443719 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179769 NZ_CP063943:c1443726-1443581 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References