Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 424724..424869 Replicon chromosome
Accession NZ_CP063939
Organism Klebsiella pneumoniae strain BM343

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 424760..424862 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 424724..424869 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA62_RS01950 419854..421914 + 2061 WP_004151449.1 oligopeptidase B -
ISA62_RS01955 421918..422577 - 660 WP_002911407.1 exodeoxyribonuclease X -
ISA62_RS01960 422656..422886 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ISA62_RS01965 422999..423373 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ISA62_RS01970 423377..424246 + 870 WP_023316211.1 copper homeostasis membrane protein CopD -
ISA62_RS01975 424263..424601 + 339 WP_002911404.1 YebY family protein -
- 424724..424869 - 146 - - Antitoxin
- 424760..424862 + 103 - - Toxin
ISA62_RS01980 425237..425380 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ISA62_RS01985 425485..426453 - 969 WP_004151446.1 VirK/YbjX family protein -
ISA62_RS01990 426610..427263 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
ISA62_RS01995 427260..427451 - 192 WP_002911395.1 YebW family protein -
ISA62_RS02000 427549..427788 - 240 WP_002911393.1 YebV family protein -
ISA62_RS02005 427904..429337 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179735 NZ_CP063939:424760-424862 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179735 NZ_CP063939:c424869-424724 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References