Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 415383..415528 Replicon chromosome
Accession NZ_CP063936
Organism Klebsiella pneumoniae strain BS317-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 415390..415492 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 415383..415528 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA63_RS02110 410915..412348 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA63_RS02115 412464..412703 + 240 WP_002911393.1 YebV family protein -
ISA63_RS02120 412801..412992 + 192 WP_002911395.1 YebW family protein -
ISA63_RS02125 412989..413642 - 654 WP_031589291.1 protein-serine/threonine phosphatase -
ISA63_RS02130 413799..414767 + 969 WP_162472361.1 VirK/YbjX family protein -
ISA63_RS02135 414872..415015 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 415383..415528 + 146 - - Antitoxin
- 415390..415492 - 103 - - Toxin
ISA63_RS02140 415651..415989 - 339 WP_002911404.1 YebY family protein -
ISA63_RS02145 416006..416875 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISA63_RS02150 416879..417253 - 375 WP_004151448.1 CopC domain-containing protein YobA -
ISA63_RS02155 417366..417596 + 231 WP_002911406.1 DNA polymerase III subunit theta -
ISA63_RS02160 417675..418334 + 660 WP_002911407.1 exodeoxyribonuclease X -
ISA63_RS02165 418338..420398 - 2061 WP_032444542.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179717 NZ_CP063936:c415492-415390 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179717 NZ_CP063936:415383-415528 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References