Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1307272..1307416 Replicon chromosome
Accession NZ_CP063933
Organism Klebsiella variicola strain BS369-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1307278..1307380 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1307272..1307416 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA65_RS06435 1302794..1304227 + 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA65_RS06440 1304343..1304582 + 240 WP_002911393.1 YebV family protein -
ISA65_RS06445 1304680..1304871 + 192 WP_002911395.1 YebW family protein -
ISA65_RS06450 1304868..1305521 - 654 WP_012967753.1 protein-serine/threonine phosphatase -
ISA65_RS06455 1305678..1306646 + 969 WP_194387062.1 VirK/YbjX family protein -
ISA65_RS06460 1306750..1306893 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 1307272..1307416 + 145 - - Antitoxin
- 1307278..1307380 - 103 - - Toxin
ISA65_RS06465 1307538..1307876 - 339 WP_008804271.1 YebY family protein -
ISA65_RS06470 1307893..1308762 - 870 WP_012541262.1 copper homeostasis membrane protein CopD -
ISA65_RS06475 1308766..1309140 - 375 WP_016161388.1 CopC domain-containing protein YobA -
ISA65_RS06480 1309254..1309484 + 231 WP_012541260.1 DNA polymerase III subunit theta -
ISA65_RS06485 1309563..1310222 + 660 WP_008804267.1 exodeoxyribonuclease X -
ISA65_RS06490 1310226..1312286 - 2061 WP_032746815.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179679 NZ_CP063933:c1307380-1307278 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179679 NZ_CP063933:1307272-1307416 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References