Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3468817..3468961 Replicon chromosome
Accession NZ_CP063932
Organism Klebsiella variicola strain BS375-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3468823..3468925 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3468817..3468961 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA66_RS16670 3464339..3465772 + 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA66_RS16675 3465888..3466127 + 240 WP_002911393.1 YebV family protein -
ISA66_RS16680 3466225..3466416 + 192 WP_002911395.1 YebW family protein -
ISA66_RS16685 3466413..3467066 - 654 WP_012967753.1 protein-serine/threonine phosphatase -
ISA66_RS16690 3467223..3468191 + 969 WP_194387062.1 VirK/YbjX family protein -
ISA66_RS16695 3468295..3468438 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 3468817..3468961 + 145 - - Antitoxin
- 3468823..3468925 - 103 - - Toxin
ISA66_RS16700 3469083..3469421 - 339 WP_008804271.1 YebY family protein -
ISA66_RS16705 3469438..3470307 - 870 WP_012541262.1 copper homeostasis membrane protein CopD -
ISA66_RS16710 3470311..3470685 - 375 WP_016161388.1 CopC domain-containing protein YobA -
ISA66_RS16715 3470799..3471029 + 231 WP_012541260.1 DNA polymerase III subunit theta -
ISA66_RS16720 3471108..3471767 + 660 WP_008804267.1 exodeoxyribonuclease X -
ISA66_RS16725 3471771..3473831 - 2061 WP_032746815.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179665 NZ_CP063932:c3468925-3468823 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179665 NZ_CP063932:3468817-3468961 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References