Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4513900..4514045 | Replicon | chromosome |
| Accession | NZ_CP063930 | ||
| Organism | Klebsiella pneumoniae strain M186-2 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4513936..4514038 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4513900..4514045 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISA67_RS21620 | 4509030..4511090 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| ISA67_RS21625 | 4511094..4511753 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| ISA67_RS21630 | 4511832..4512062 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| ISA67_RS21635 | 4512175..4512549 | + | 375 | WP_101817068.1 | CopC domain-containing protein YobA | - |
| ISA67_RS21640 | 4512553..4513422 | + | 870 | WP_023286639.1 | copper homeostasis membrane protein CopD | - |
| ISA67_RS21645 | 4513439..4513777 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 4513900..4514045 | - | 146 | - | - | Antitoxin |
| - | 4513936..4514038 | + | 103 | - | - | Toxin |
| ISA67_RS21650 | 4514412..4514555 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| ISA67_RS21655 | 4514660..4515628 | - | 969 | WP_074194451.1 | VirK/YbjX family protein | - |
| ISA67_RS21660 | 4515785..4516438 | + | 654 | WP_023280291.1 | protein-serine/threonine phosphatase | - |
| ISA67_RS21665 | 4516435..4516626 | - | 192 | WP_002911395.1 | YebW family protein | - |
| ISA67_RS21670 | 4516724..4516963 | - | 240 | WP_002911393.1 | YebV family protein | - |
| ISA67_RS21675 | 4517079..4518512 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T179645 NZ_CP063930:4513936-4514038 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT179645 NZ_CP063930:c4514045-4513900 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT