Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4513900..4514045 Replicon chromosome
Accession NZ_CP063930
Organism Klebsiella pneumoniae strain M186-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4513936..4514038 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4513900..4514045 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA67_RS21620 4509030..4511090 + 2061 WP_004151449.1 oligopeptidase B -
ISA67_RS21625 4511094..4511753 - 660 WP_002911407.1 exodeoxyribonuclease X -
ISA67_RS21630 4511832..4512062 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ISA67_RS21635 4512175..4512549 + 375 WP_101817068.1 CopC domain-containing protein YobA -
ISA67_RS21640 4512553..4513422 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
ISA67_RS21645 4513439..4513777 + 339 WP_016529031.1 YebY family protein -
- 4513900..4514045 - 146 - - Antitoxin
- 4513936..4514038 + 103 - - Toxin
ISA67_RS21650 4514412..4514555 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ISA67_RS21655 4514660..4515628 - 969 WP_074194451.1 VirK/YbjX family protein -
ISA67_RS21660 4515785..4516438 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
ISA67_RS21665 4516435..4516626 - 192 WP_002911395.1 YebW family protein -
ISA67_RS21670 4516724..4516963 - 240 WP_002911393.1 YebV family protein -
ISA67_RS21675 4517079..4518512 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179645 NZ_CP063930:4513936-4514038 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179645 NZ_CP063930:c4514045-4513900 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References