Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5164458..5164603 Replicon chromosome
Accession NZ_CP063927
Organism Klebsiella pneumoniae strain S183-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5164494..5164596 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5164458..5164603 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA68_RS24900 5159588..5161648 + 2061 WP_004151449.1 oligopeptidase B -
ISA68_RS24905 5161652..5162311 - 660 WP_002911407.1 exodeoxyribonuclease X -
ISA68_RS24910 5162390..5162620 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ISA68_RS24915 5162733..5163107 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ISA68_RS24920 5163111..5163980 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISA68_RS24925 5163997..5164335 + 339 WP_016529031.1 YebY family protein -
- 5164458..5164603 - 146 - - Antitoxin
- 5164494..5164596 + 103 - - Toxin
ISA68_RS24930 5164971..5165114 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ISA68_RS24935 5165219..5166187 - 969 WP_074426446.1 VirK/YbjX family protein -
ISA68_RS24940 5166344..5166997 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
ISA68_RS24945 5166994..5167185 - 192 WP_002911395.1 YebW family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179608 NZ_CP063927:5164494-5164596 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179608 NZ_CP063927:c5164603-5164458 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References