Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 343165..343310 Replicon chromosome
Accession NZ_CP063925
Organism Klebsiella pneumoniae strain S210-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 343172..343274 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 343165..343310 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA70_RS01675 338697..340130 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA70_RS01680 340246..340485 + 240 WP_002911393.1 YebV family protein -
ISA70_RS01685 340583..340774 + 192 WP_002911395.1 YebW family protein -
ISA70_RS01690 340771..341424 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
ISA70_RS01695 341581..342549 + 969 WP_074421963.1 VirK/YbjX family protein -
ISA70_RS01700 342654..342797 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 343165..343310 + 146 - - Antitoxin
- 343172..343274 - 103 - - Toxin
ISA70_RS01705 343433..343771 - 339 WP_002911404.1 YebY family protein -
ISA70_RS01710 343788..344657 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISA70_RS01715 344661..345035 - 375 WP_016529032.1 CopC domain-containing protein YobA -
ISA70_RS01720 345148..345378 + 231 WP_002911406.1 DNA polymerase III subunit theta -
ISA70_RS01725 345457..346116 + 660 WP_002911407.1 exodeoxyribonuclease X -
ISA70_RS01730 346120..348180 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179565 NZ_CP063925:c343274-343172 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179565 NZ_CP063925:343165-343310 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References