Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1143275..1143420 | Replicon | chromosome |
| Accession | NZ_CP063922 | ||
| Organism | Klebsiella pneumoniae strain BM338-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1143282..1143384 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1143275..1143420 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISA71_RS05685 | 1138807..1140240 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| ISA71_RS05690 | 1140356..1140595 | + | 240 | WP_002911393.1 | YebV family protein | - |
| ISA71_RS05695 | 1140693..1140884 | + | 192 | WP_002911395.1 | YebW family protein | - |
| ISA71_RS05700 | 1140881..1141534 | - | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| ISA71_RS05705 | 1141691..1142659 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| ISA71_RS05710 | 1142764..1142907 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 1143275..1143420 | + | 146 | - | - | Antitoxin |
| - | 1143282..1143384 | - | 103 | - | - | Toxin |
| ISA71_RS05715 | 1143543..1143881 | - | 339 | WP_002911404.1 | YebY family protein | - |
| ISA71_RS05720 | 1143898..1144767 | - | 870 | WP_004891049.1 | copper homeostasis membrane protein CopD | - |
| ISA71_RS05725 | 1144771..1145145 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| ISA71_RS05730 | 1145258..1145488 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| ISA71_RS05735 | 1145567..1146226 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| ISA71_RS05740 | 1146230..1148290 | - | 2061 | WP_004148850.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T179541 NZ_CP063922:c1143384-1143282 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT179541 NZ_CP063922:1143275-1143420 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
