Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4719120..4719265 | Replicon | chromosome |
| Accession | NZ_CP063919 | ||
| Organism | Klebsiella pneumoniae strain BM337-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4719127..4719229 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4719120..4719265 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISA74_RS22905 | 4714652..4716085 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| ISA74_RS22910 | 4716201..4716440 | + | 240 | WP_002911393.1 | YebV family protein | - |
| ISA74_RS22915 | 4716538..4716729 | + | 192 | WP_002911395.1 | YebW family protein | - |
| ISA74_RS22920 | 4716726..4717379 | - | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| ISA74_RS22925 | 4717536..4718504 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| ISA74_RS22930 | 4718609..4718752 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 4719120..4719265 | + | 146 | - | - | Antitoxin |
| - | 4719127..4719229 | - | 103 | - | - | Toxin |
| ISA74_RS22935 | 4719388..4719726 | - | 339 | WP_002911404.1 | YebY family protein | - |
| ISA74_RS22940 | 4719743..4720612 | - | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| ISA74_RS22945 | 4720616..4720990 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| ISA74_RS22950 | 4721103..4721333 | + | 231 | WP_025860700.1 | DNA polymerase III subunit theta | - |
| ISA74_RS22955 | 4721412..4722071 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| ISA74_RS22960 | 4722075..4724135 | - | 2061 | WP_004148850.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T179512 NZ_CP063919:c4719229-4719127 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT179512 NZ_CP063919:4719120-4719265 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
