Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4487270..4487414 Replicon chromosome
Accession NZ_CP063916
Organism Klebsiella variicola strain BS327-2-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4487276..4487378 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4487270..4487414 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA76_RS21735 4482792..4484225 + 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA76_RS21740 4484341..4484580 + 240 WP_002911393.1 YebV family protein -
ISA76_RS21745 4484678..4484869 + 192 WP_002911395.1 YebW family protein -
ISA76_RS21750 4484866..4485519 - 654 WP_012967753.1 protein-serine/threonine phosphatase -
ISA76_RS21755 4485676..4486644 + 969 WP_194387062.1 VirK/YbjX family protein -
ISA76_RS21760 4486748..4486891 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 4487270..4487414 + 145 - - Antitoxin
- 4487276..4487378 - 103 - - Toxin
ISA76_RS21765 4487536..4487874 - 339 WP_008804271.1 YebY family protein -
ISA76_RS21770 4487891..4488760 - 870 WP_012541262.1 copper homeostasis membrane protein CopD -
ISA76_RS21775 4488764..4489138 - 375 WP_016161388.1 CopC domain-containing protein YobA -
ISA76_RS21780 4489252..4489482 + 231 WP_012541260.1 DNA polymerase III subunit theta -
ISA76_RS21785 4489561..4490220 + 660 WP_008804267.1 exodeoxyribonuclease X -
ISA76_RS21790 4490224..4492284 - 2061 WP_032746815.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179475 NZ_CP063916:c4487378-4487276 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179475 NZ_CP063916:4487270-4487414 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References