Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4102834..4102979 Replicon chromosome
Accession NZ_CP063913
Organism Klebsiella pneumoniae strain BM336-2-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4102870..4102972 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4102834..4102979 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA78_RS19560 4097964..4100024 + 2061 WP_004151449.1 oligopeptidase B -
ISA78_RS19565 4100028..4100687 - 660 WP_002911407.1 exodeoxyribonuclease X -
ISA78_RS19570 4100766..4100996 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ISA78_RS19575 4101109..4101483 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ISA78_RS19580 4101487..4102356 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
ISA78_RS19585 4102373..4102711 + 339 WP_002911404.1 YebY family protein -
- 4102834..4102979 - 146 - - Antitoxin
- 4102870..4102972 + 103 - - Toxin
ISA78_RS19590 4103347..4103490 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ISA78_RS19595 4103595..4104563 - 969 WP_014907334.1 VirK/YbjX family protein -
ISA78_RS19600 4104720..4105373 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
ISA78_RS19605 4105370..4105561 - 192 WP_002911395.1 YebW family protein -
ISA78_RS19610 4105659..4105898 - 240 WP_002911393.1 YebV family protein -
ISA78_RS19615 4106014..4107447 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179439 NZ_CP063913:4102870-4102972 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179439 NZ_CP063913:c4102979-4102834 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References