Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 801655..801799 Replicon chromosome
Accession NZ_CP063911
Organism Klebsiella variicola strain M186-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 801661..801763 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 801655..801799 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA80_RS03940 797178..798611 + 1434 WP_048268569.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA80_RS03945 798727..798966 + 240 WP_002911393.1 YebV family protein -
ISA80_RS03950 799064..799255 + 192 WP_002911395.1 YebW family protein -
ISA80_RS03955 799252..799905 - 654 WP_008804273.1 protein-serine/threonine phosphatase -
ISA80_RS03960 800061..801029 + 969 WP_162493241.1 VirK/YbjX family protein -
ISA80_RS03965 801133..801276 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 801655..801799 + 145 - - Antitoxin
- 801661..801763 - 103 - - Toxin
ISA80_RS03970 801921..802259 - 339 WP_008804271.1 YebY family protein -
ISA80_RS03975 802276..803145 - 870 WP_012541262.1 copper homeostasis membrane protein CopD -
ISA80_RS03980 803149..803523 - 375 WP_012541261.1 CopC domain-containing protein YobA -
ISA80_RS03985 803637..803867 + 231 WP_012541260.1 DNA polymerase III subunit theta -
ISA80_RS03990 803946..804605 + 660 WP_012541259.1 exodeoxyribonuclease X -
ISA80_RS03995 804609..806669 - 2061 WP_012541258.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179396 NZ_CP063911:c801763-801661 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179396 NZ_CP063911:801655-801799 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References