Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2113248..2113393 | Replicon | chromosome |
| Accession | NZ_CP063908 | ||
| Organism | Klebsiella pneumoniae strain M212-2 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2113255..2113357 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2113248..2113393 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISA82_RS10240 | 2108780..2110213 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| ISA82_RS10245 | 2110329..2110568 | + | 240 | WP_002911393.1 | YebV family protein | - |
| ISA82_RS10250 | 2110666..2110857 | + | 192 | WP_002911395.1 | YebW family protein | - |
| ISA82_RS10255 | 2110854..2111507 | - | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| ISA82_RS10260 | 2111664..2112632 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| ISA82_RS10265 | 2112737..2112880 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 2113248..2113393 | + | 146 | - | - | Antitoxin |
| - | 2113255..2113357 | - | 103 | - | - | Toxin |
| ISA82_RS10270 | 2113516..2113854 | - | 339 | WP_002911404.1 | YebY family protein | - |
| ISA82_RS10275 | 2113871..2114740 | - | 870 | WP_014907333.1 | copper homeostasis membrane protein CopD | - |
| ISA82_RS10280 | 2114744..2115118 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| ISA82_RS10285 | 2115231..2115461 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| ISA82_RS10290 | 2115540..2116199 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| ISA82_RS10295 | 2116203..2118263 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T179361 NZ_CP063908:c2113357-2113255 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT179361 NZ_CP063908:2113248-2113393 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
