Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 863491..863636 Replicon chromosome
Accession NZ_CP063906
Organism Klebsiella pneumoniae strain BM327-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 863498..863600 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 863491..863636 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA83_RS04365 859023..860456 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA83_RS04370 860572..860811 + 240 WP_002911393.1 YebV family protein -
ISA83_RS04375 860909..861100 + 192 WP_002911395.1 YebW family protein -
ISA83_RS04380 861097..861750 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
ISA83_RS04385 861907..862875 + 969 WP_014907334.1 VirK/YbjX family protein -
ISA83_RS04390 862980..863123 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 863491..863636 + 146 - - Antitoxin
- 863498..863600 - 103 - - Toxin
ISA83_RS04395 863759..864097 - 339 WP_002911404.1 YebY family protein -
ISA83_RS04400 864114..864983 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISA83_RS04405 864987..865361 - 375 WP_004151448.1 CopC domain-containing protein YobA -
ISA83_RS04410 865474..865704 + 231 WP_025860700.1 DNA polymerase III subunit theta -
ISA83_RS04415 865783..866442 + 660 WP_002911407.1 exodeoxyribonuclease X -
ISA83_RS04420 866446..868506 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179338 NZ_CP063906:c863600-863498 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179338 NZ_CP063906:863491-863636 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References