Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 667800..667945 Replicon chromosome
Accession NZ_CP063904
Organism Klebsiella pneumoniae strain BM334-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 667836..667938 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 667800..667945 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA84_RS03200 662930..664990 + 2061 WP_004151449.1 oligopeptidase B -
ISA84_RS03205 664994..665653 - 660 WP_002911407.1 exodeoxyribonuclease X -
ISA84_RS03210 665732..665962 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ISA84_RS03215 666075..666449 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ISA84_RS03220 666453..667322 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISA84_RS03225 667339..667677 + 339 WP_002911404.1 YebY family protein -
- 667800..667945 - 146 - - Antitoxin
- 667836..667938 + 103 - - Toxin
ISA84_RS03230 668312..668455 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ISA84_RS03235 668560..669528 - 969 WP_004151446.1 VirK/YbjX family protein -
ISA84_RS03240 669685..670338 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
ISA84_RS03245 670335..670526 - 192 WP_002911395.1 YebW family protein -
ISA84_RS03250 670624..670863 - 240 WP_002911393.1 YebV family protein -
ISA84_RS03255 670979..672412 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179318 NZ_CP063904:667836-667938 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179318 NZ_CP063904:c667945-667800 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References