Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 1863040..1863553 | Replicon | chromosome |
| Accession | NZ_CP063896 | ||
| Organism | Klebsiella quasipneumoniae strain BS419-1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A663BE04 |
| Locus tag | ISA88_RS08960 | Protein ID | WP_017900571.1 |
| Coordinates | 1863040..1863321 (-) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | ISA88_RS08965 | Protein ID | WP_048322784.1 |
| Coordinates | 1863311..1863553 (-) | Length | 81 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISA88_RS08950 | 1860051..1862189 | + | 2139 | WP_080838453.1 | anaerobic ribonucleoside-triphosphate reductase | - |
| ISA88_RS08955 | 1862572..1863036 | + | 465 | WP_023319597.1 | anaerobic ribonucleoside-triphosphate reductase-activating protein | - |
| ISA88_RS08960 | 1863040..1863321 | - | 282 | WP_017900571.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| ISA88_RS08965 | 1863311..1863553 | - | 243 | WP_048322784.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| ISA88_RS08970 | 1863631..1865541 | - | 1911 | WP_004206509.1 | BglG family transcription antiterminator | - |
| ISA88_RS08975 | 1865564..1866718 | - | 1155 | WP_065697356.1 | lactonase family protein | - |
| ISA88_RS08980 | 1866881..1867621 | - | 741 | WP_004206507.1 | KDGP aldolase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 11082.93 Da Isoelectric Point: 10.4123
>T179255 WP_017900571.1 NZ_CP063896:c1863321-1863040 [Klebsiella quasipneumoniae]
MTYELEFDPRAWREWQLGETVKKQFKNKLQQIVQNPRIESARLSDLPDCYKIKLKASGYRLVYQVRDRVVVVYVIAIGKR
EKAAVYHQANKRL
MTYELEFDPRAWREWQLGETVKKQFKNKLQQIVQNPRIESARLSDLPDCYKIKLKASGYRLVYQVRDRVVVVYVIAIGKR
EKAAVYHQANKRL
Download Length: 282 bp
>T179255 NZ_CP084654:c4857410-4856523 [Pectobacterium versatile]
ATGCTGAAGCAACAAATTCGCCAAATTGTCCAGTCAAACCCTGACTATGCCGCAGTGACACCCGTCATAGAAAAAGAGAT
CTTGCATCATGACATTATGGATGTGCTGATAAAACAGGGCGTCATGCAGCGGTTAACGTTCATTGGCGGCACCTCATTAC
GAATGTGTTACAACAGCAGCAGGCTATCAGAAGATCTTGATTTCAATGGTGGTCATGATTTCAAGCCCTCAGCGTTTGAG
GGGCTGGAGTCCGAAATCCAAACCTATATTCAGAACAAGTATGAAACCGAGGTTTGGGTAAACAAACCTTCTGGCGAGCA
GCAAGGGGATACCGTTTCTTGGAAAATTAGTATCGTAAAAGACGCTAATCGTCCTGATTTGCCACGGCAAAAAATGCATA
TTGACGTCTGTGCTATTCCGTCATTTGATATTGAAAAGCGCCCGCTAATCAATCATTACGACATCGTTGTTCCGACTGAA
GGGATCTTGGTTCCGGTACAGTCGTTACAAGAAACATTGGCCGATAAGTTGATCGCGTTAGCGTATCGGGCAAGACGTAT
TAAACCTCGTGATATCTGGGATATTGTTTGGATTAAGCAGCGCGGTATTGATTTATCCAAGACACTGGTTGAAAAGAAGC
TCACCGCCAGACAGAAGCAAACAGAAGACTTTCGACAGGCGCTGTCTATTCAGTTAGCCAAGCTAATGTCGGAAGATGAA
GTCCGTGACGACTTCAATATGGAAATGAGCCGTTTTATCTCTAAGCAAATTAAAGAGAGAACCCTCGATAATCCTGCATA
TTGGGCTTATGTTCAGGGCGAGGTACATGCCATCGCGTCTGAGTTACTGAATGACGGAACACCAAAAAATCCATTTGATA
TGGGTTAG
ATGCTGAAGCAACAAATTCGCCAAATTGTCCAGTCAAACCCTGACTATGCCGCAGTGACACCCGTCATAGAAAAAGAGAT
CTTGCATCATGACATTATGGATGTGCTGATAAAACAGGGCGTCATGCAGCGGTTAACGTTCATTGGCGGCACCTCATTAC
GAATGTGTTACAACAGCAGCAGGCTATCAGAAGATCTTGATTTCAATGGTGGTCATGATTTCAAGCCCTCAGCGTTTGAG
GGGCTGGAGTCCGAAATCCAAACCTATATTCAGAACAAGTATGAAACCGAGGTTTGGGTAAACAAACCTTCTGGCGAGCA
GCAAGGGGATACCGTTTCTTGGAAAATTAGTATCGTAAAAGACGCTAATCGTCCTGATTTGCCACGGCAAAAAATGCATA
TTGACGTCTGTGCTATTCCGTCATTTGATATTGAAAAGCGCCCGCTAATCAATCATTACGACATCGTTGTTCCGACTGAA
GGGATCTTGGTTCCGGTACAGTCGTTACAAGAAACATTGGCCGATAAGTTGATCGCGTTAGCGTATCGGGCAAGACGTAT
TAAACCTCGTGATATCTGGGATATTGTTTGGATTAAGCAGCGCGGTATTGATTTATCCAAGACACTGGTTGAAAAGAAGC
TCACCGCCAGACAGAAGCAAACAGAAGACTTTCGACAGGCGCTGTCTATTCAGTTAGCCAAGCTAATGTCGGAAGATGAA
GTCCGTGACGACTTCAATATGGAAATGAGCCGTTTTATCTCTAAGCAAATTAAAGAGAGAACCCTCGATAATCCTGCATA
TTGGGCTTATGTTCAGGGCGAGGTACATGCCATCGCGTCTGAGTTACTGAATGACGGAACACCAAAAAATCCATTTGATA
TGGGTTAG
Antitoxin
Download Length: 81 a.a. Molecular weight: 9117.61 Da Isoelectric Point: 5.1486
>AT179255 WP_048322784.1 NZ_CP063896:c1863553-1863311 [Klebsiella quasipneumoniae]
MATLNVRLDDKLKKEAYAVLEKLDMTPTEAVRLLFQYIAENGRMPVKSMTISDGEAALLRTVRERLENPRPEVKVSLDDL
MATLNVRLDDKLKKEAYAVLEKLDMTPTEAVRLLFQYIAENGRMPVKSMTISDGEAALLRTVRERLENPRPEVKVSLDDL
Download Length: 243 bp
>AT179255 NZ_CP084654:c4857963-4857439 [Pectobacterium versatile]
ATGGCTAAATCTGATGAGCTATTAAACGCGTTGGCCAAAGCAGTGAACGCCGGCGGCGGCATTCACAGTGTAACAGAGCT
GGCTTTTATGCAGGGTGTGCCTTGTGACTCAGCCTTTAGAAAATTCCTGGCAGATTGCGTAAAGAAGGGGTTGCTAAGAC
GAGTGGTGAAAGGCTTCTATGAAAGTGTTATTACACCACCTGAGCCTGAGACTGCCATTTATAAAATCATCAAAAAGTTG
CGCAGCGGCGTATTGAGCTACATCAGCTTAGAAAGTCAGCTCAGTCATACCGGTGATATTTCACAAGTTGTGATGGGTAG
AGTCACTGTGGTGACTAAAGGTCGAAGTGGTTGTTTTGATACGCCTTATGGCGTGATCGAGTTTACCCATACTAAAAAGC
CAGTCGAGCAAATTGCACCTAATTTGTATTATGACCCCGACATCAAAATGTATCGCGCATACAAGGAACAAGCGATTGCA
GATCTAAAGCACTGCCAGCGCAATCTACATATGTTGGAGAGCTAA
ATGGCTAAATCTGATGAGCTATTAAACGCGTTGGCCAAAGCAGTGAACGCCGGCGGCGGCATTCACAGTGTAACAGAGCT
GGCTTTTATGCAGGGTGTGCCTTGTGACTCAGCCTTTAGAAAATTCCTGGCAGATTGCGTAAAGAAGGGGTTGCTAAGAC
GAGTGGTGAAAGGCTTCTATGAAAGTGTTATTACACCACCTGAGCCTGAGACTGCCATTTATAAAATCATCAAAAAGTTG
CGCAGCGGCGTATTGAGCTACATCAGCTTAGAAAGTCAGCTCAGTCATACCGGTGATATTTCACAAGTTGTGATGGGTAG
AGTCACTGTGGTGACTAAAGGTCGAAGTGGTTGTTTTGATACGCCTTATGGCGTGATCGAGTTTACCCATACTAAAAAGC
CAGTCGAGCAAATTGCACCTAATTTGTATTATGACCCCGACATCAAAATGTATCGCGCATACAAGGAACAAGCGATTGCA
GATCTAAAGCACTGCCAGCGCAATCTACATATGTTGGAGAGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|