Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 507131..507276 Replicon chromosome
Accession NZ_CP063890
Organism Klebsiella pneumoniae strain BS433-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 507138..507240 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 507131..507276 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISB10_RS02520 502663..504096 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISB10_RS02525 504212..504451 + 240 WP_002911393.1 YebV family protein -
ISB10_RS02530 504549..504740 + 192 WP_002911395.1 YebW family protein -
ISB10_RS02535 504737..505390 - 654 WP_194428964.1 protein-serine/threonine phosphatase -
ISB10_RS02540 505547..506515 + 969 WP_014907334.1 VirK/YbjX family protein -
ISB10_RS02545 506620..506763 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 507131..507276 + 146 - - Antitoxin
- 507138..507240 - 103 - - Toxin
ISB10_RS02550 507399..507737 - 339 WP_002911404.1 YebY family protein -
ISB10_RS02555 507754..508623 - 870 WP_014907333.1 copper homeostasis membrane protein CopD -
ISB10_RS02560 508627..509001 - 375 WP_004151448.1 CopC domain-containing protein YobA -
ISB10_RS02565 509114..509344 + 231 WP_002911406.1 DNA polymerase III subunit theta -
ISB10_RS02570 509423..510082 + 660 WP_002911407.1 exodeoxyribonuclease X -
ISB10_RS02575 510086..512146 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179235 NZ_CP063890:c507240-507138 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179235 NZ_CP063890:507131-507276 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References