Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5233588..5233733 Replicon chromosome
Accession NZ_CP063885
Organism Klebsiella pneumoniae strain BS361-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5233595..5233697 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5233588..5233733 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISB15_RS25385 5229120..5230553 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISB15_RS25390 5230669..5230908 + 240 WP_002911393.1 YebV family protein -
ISB15_RS25395 5231006..5231197 + 192 WP_002911395.1 YebW family protein -
ISB15_RS25400 5231194..5231847 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
ISB15_RS25405 5232004..5232972 + 969 WP_014907334.1 VirK/YbjX family protein -
ISB15_RS25410 5233077..5233220 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5233588..5233733 + 146 - - Antitoxin
- 5233595..5233697 - 103 - - Toxin
ISB15_RS25415 5233856..5234194 - 339 WP_002911404.1 YebY family protein -
ISB15_RS25420 5234211..5235080 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISB15_RS25425 5235084..5235458 - 375 WP_004151448.1 CopC domain-containing protein YobA -
ISB15_RS25430 5235571..5235801 + 231 WP_025860700.1 DNA polymerase III subunit theta -
ISB15_RS25435 5235880..5236539 + 660 WP_002911407.1 exodeoxyribonuclease X -
ISB15_RS25440 5236543..5238603 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179195 NZ_CP063885:c5233697-5233595 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179195 NZ_CP063885:5233588-5233733 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References