Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4412051..4412196 Replicon chromosome
Accession NZ_CP063881
Organism Klebsiella pneumoniae strain S90-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4412087..4412189 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4412051..4412196 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD49_RS21510 4407181..4409241 + 2061 WP_047694778.1 oligopeptidase B -
IOD49_RS21515 4409245..4409904 - 660 WP_102000926.1 exodeoxyribonuclease X -
IOD49_RS21520 4409983..4410213 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IOD49_RS21525 4410326..4410700 + 375 WP_023285314.1 CopC domain-containing protein YobA -
IOD49_RS21530 4410704..4411573 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
IOD49_RS21535 4411590..4411928 + 339 WP_002911404.1 YebY family protein -
- 4412051..4412196 - 146 - - Antitoxin
- 4412087..4412189 + 103 - - Toxin
IOD49_RS21540 4412564..4412707 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IOD49_RS21545 4412812..4413780 - 969 WP_004151446.1 VirK/YbjX family protein -
IOD49_RS21550 4413937..4414590 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
IOD49_RS21555 4414587..4414778 - 192 WP_002911395.1 YebW family protein -
IOD49_RS21560 4414876..4415115 - 240 WP_002911393.1 YebV family protein -
IOD49_RS21565 4415231..4416664 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179171 NZ_CP063881:4412087-4412189 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179171 NZ_CP063881:c4412196-4412051 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References