Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1345400..1345545 Replicon chromosome
Accession NZ_CP063865
Organism Klebsiella pneumoniae strain S130-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1345407..1345509 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1345400..1345545 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD48_RS06920 1340932..1342365 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IOD48_RS06925 1342481..1342720 + 240 WP_002911393.1 YebV family protein -
IOD48_RS06930 1342818..1343009 + 192 WP_002911395.1 YebW family protein -
IOD48_RS06935 1343006..1343659 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
IOD48_RS06940 1343816..1344784 + 969 WP_004151446.1 VirK/YbjX family protein -
IOD48_RS06945 1344889..1345032 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1345400..1345545 + 146 - - Antitoxin
- 1345407..1345509 - 103 - - Toxin
IOD48_RS06950 1345668..1346006 - 339 WP_002911404.1 YebY family protein -
IOD48_RS06955 1346023..1346892 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
IOD48_RS06960 1346896..1347270 - 375 WP_004151448.1 CopC domain-containing protein YobA -
IOD48_RS06965 1347383..1347613 + 231 WP_002911406.1 DNA polymerase III subunit theta -
IOD48_RS06970 1347692..1348351 + 660 WP_002911407.1 exodeoxyribonuclease X -
IOD48_RS06975 1348355..1350415 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179050 NZ_CP063865:c1345509-1345407 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179050 NZ_CP063865:1345400-1345545 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References