Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3478595..3478740 Replicon chromosome
Accession NZ_CP063863
Organism Klebsiella pneumoniae strain M63-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3478631..3478733 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3478595..3478740 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD47_RS16620 3473725..3475785 + 2061 WP_130972366.1 oligopeptidase B -
IOD47_RS16625 3475789..3476448 - 660 WP_002911407.1 exodeoxyribonuclease X -
IOD47_RS16630 3476527..3476757 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IOD47_RS16635 3476870..3477244 + 375 WP_130972367.1 CopC domain-containing protein YobA -
IOD47_RS16640 3477248..3478117 + 870 WP_200995458.1 copper homeostasis membrane protein CopD -
IOD47_RS16645 3478134..3478472 + 339 WP_016529031.1 YebY family protein -
- 3478595..3478740 - 146 - - Antitoxin
- 3478631..3478733 + 103 - - Toxin
IOD47_RS16650 3479109..3479252 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IOD47_RS16655 3479357..3480325 - 969 WP_074185275.1 DUF535 family protein -
IOD47_RS16660 3480482..3481135 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
IOD47_RS16665 3481132..3481323 - 192 WP_002911395.1 YebW family protein -
IOD47_RS16670 3481421..3481660 - 240 WP_002911393.1 YebV family protein -
IOD47_RS16675 3481776..3483209 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179039 NZ_CP063863:3478631-3478733 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179039 NZ_CP063863:c3478740-3478595 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References