Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4527221..4527366 Replicon chromosome
Accession NZ_CP063851
Organism Klebsiella pneumoniae strain M1023-4Ar

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4527257..4527359 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4527221..4527366 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD43_RS21820 4522351..4524411 + 2061 WP_004151449.1 oligopeptidase B -
IOD43_RS21825 4524415..4525074 - 660 WP_021440386.1 exodeoxyribonuclease X -
IOD43_RS21830 4525153..4525383 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IOD43_RS21835 4525496..4525870 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IOD43_RS21840 4525874..4526743 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
IOD43_RS21845 4526760..4527098 + 339 WP_002911404.1 YebY family protein -
- 4527221..4527366 - 146 - - Antitoxin
- 4527257..4527359 + 103 - - Toxin
IOD43_RS21850 4527735..4527878 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IOD43_RS21855 4527983..4528951 - 969 WP_004151446.1 VirK/YbjX family protein -
IOD43_RS21860 4529108..4529761 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
IOD43_RS21865 4529758..4529949 - 192 WP_002911395.1 YebW family protein -
IOD43_RS21870 4530047..4530286 - 240 WP_002911393.1 YebV family protein -
IOD43_RS21875 4530402..4531835 - 1434 WP_194315361.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T178969 NZ_CP063851:4527257-4527359 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT178969 NZ_CP063851:c4527366-4527221 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References