Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2082988..2083793 Replicon chromosome
Accession NZ_CP063849
Organism Paludibaculum fermentans strain P105

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag IRI77_RS08270 Protein ID WP_194451600.1
Coordinates 2082988..2083518 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag IRI77_RS08275 Protein ID WP_194451601.1
Coordinates 2083515..2083793 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRI77_RS08255 2078989..2079279 + 291 WP_194451597.1 hypothetical protein -
IRI77_RS08260 2079280..2081550 - 2271 WP_194451598.1 heparinase II/III family protein -
IRI77_RS08265 2081612..2082883 + 1272 WP_194451599.1 amidohydrolase/deacetylase family metallohydrolase -
IRI77_RS08270 2082988..2083518 - 531 WP_194451600.1 GNAT family N-acetyltransferase Toxin
IRI77_RS08275 2083515..2083793 - 279 WP_194451601.1 DUF1778 domain-containing protein Antitoxin
IRI77_RS08280 2083842..2084987 - 1146 WP_194451602.1 hypothetical protein -
IRI77_RS08285 2084984..2085256 - 273 WP_194451603.1 hypothetical protein -
IRI77_RS08290 2085287..2086120 + 834 WP_194451604.1 hypothetical protein -
IRI77_RS08295 2086162..2087187 + 1026 WP_194451605.1 rod shape-determining protein -
IRI77_RS08300 2087221..2088396 + 1176 WP_194451606.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(4-89)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19219.20 Da        Isoelectric Point: 9.0864

>T178956 WP_194451600.1 NZ_CP063849:c2083518-2082988 [Paludibaculum fermentans]
MTVPSWHEEPIGKRHDRDSFQCGEPALDEFLQRYARKSHELSGAKTFLAIDDRDNKTILGFYSVSPASVRYAQTPEVVRR
GLARYDVPCFRLGRLAVDRRFQNIGLGGQLLLAAGRRCVLAAAEVGGVALLIDAKNEGVAAWYARYGAVPMAEAPLVLLL
PLATIKAALIGAGRLE

Download         Length: 531 bp

>T178956 NZ_CP084434:c713175-712825 [Staphylococcus lugdunensis]
ATGATTAGACGCGGCGATGTATATTTAGCTGATTTATCACCGGTACAAGGGTCTGAACAAGGGGGAGTAAGACCAGTTGT
CATCATTCAAAATGACACCGGTAATAAATATAGTCCAACTGTAATTGTAGCTGCAATTACTGGAAGGATTAATAAAGCGA
AAATACCCACTCATGTGGAAATAGGTAAAAAGAAATATAAGTTAGATAAAGATTCTGTTATTCTGTTAGAGCAAATACGA
ACATTAGATAAAAAAAGATTAAAAGAAAAACTTACTTATCTCTCTGAGGATAAAATGAAAGAAGTAGATCATGCCCTAGA
CATTAGTCTAGGTTTACATAACTATCATTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10386.12 Da        Isoelectric Point: 10.7450

>AT178956 WP_194451601.1 NZ_CP063849:c2083793-2083515 [Paludibaculum fermentans]
MPRTPVEDNSRMSLRIRPRDKVTLLRAVALKHTDLTEFVLQHALKAAKSVIAEAEQVELSERDSLRVLDLLENPPAPNER
LLAAAKALPRRK

Download         Length: 279 bp

>AT178956 NZ_CP084434:c713342-713172 [Staphylococcus lugdunensis]
ATGCTAACTTTTAATCAAAATCGTAGTCATAGTCTAGAACAGTCATTAAAAGAAGGGTATGCTCAGATGGCAGACCTTAA
TCTCTCCCTAGCAACAGAGGCTTTCCCAATTGAATGTGAAGCTTGTGATTGCAATGAAACTTATCTAACTTCCAATCATC
AGAGTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References