Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 213441..214030 Replicon chromosome
Accession NZ_CP063849
Organism Paludibaculum fermentans strain P105

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag IRI77_RS00795 Protein ID WP_194450194.1
Coordinates 213698..214030 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag IRI77_RS00790 Protein ID WP_194450193.1
Coordinates 213441..213698 (+) Length 86 a.a.

Genomic Context

IRI77_RS00775IRI77_RS00785IRI77_RS00790IRI77_RS00795IRI77_RS00780IRI77_RS00800IRI77_RS00805IRI77_RS00810
Location: 211154..211810 (657 bp)
Type: Others
Protein ID: WP_194450191.1
Location: 212785..213264 (480 bp)
Type: Others
Protein ID: WP_194453528.1
Location: 213441..213698 (258 bp)
Type: Antitoxin
Protein ID: WP_194450193.1
Location: 213698..214030 (333 bp)
Type: Toxin
Protein ID: WP_194450194.1
Location: 212119..212859 (741 bp)
Type: Others
Protein ID: WP_194450192.1
Location: 214168..214779 (612 bp)
Type: Others
Protein ID: WP_194450195.1
Location: 215878..216729 (852 bp)
Type: Others
Protein ID: WP_194450196.1
Location: 216726..217328 (603 bp)
Type: Others
Protein ID: WP_194450197.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IRI77_RS00775211154..211810+657WP_194450191.1hypothetical protein-
IRI77_RS00780212119..212859-741WP_194450192.1hypothetical protein-
IRI77_RS00785212785..213264+480WP_194453528.1OmpA family protein-
IRI77_RS00790213441..213698+258WP_194450193.1antitoxinAntitoxin
IRI77_RS00795213698..214030+333WP_194450194.1type II toxin-antitoxin system PemK/MazF family toxinToxin
IRI77_RS00800214168..214779-612WP_194450195.1hypothetical protein-
IRI77_RS00805215878..216729-852WP_194450196.1nucleotidyl transferase AbiEii/AbiGii toxin family protein-
IRI77_RS00810216726..217328-603WP_194450197.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--207366..23087523509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(5-78)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11739.59 Da        Isoelectric Point: 9.4892

>T178955 WP_194450194.1 NZ_CP063849:213698-214030 [Paludibaculum fermentans]
MKRCDIWLVGLDPSEGHEQKGRRRVLIVSPEAFNRVIKVPVVLPITSGGSFARTAGFAVSLSGAGTQTTGVVRCDQPRAL
DLGARGGKRLESVPDAIVEEVLARLAAIFE

Download         Length: 333 bp

>T178955 NZ_CP084434:c572672-572502 [Staphylococcus lugdunensis]
ATGTCAAAAGAAAAAAAGAGTCGTTTAAATTATCATGAGGAAGAGAATGCGATGGTTGAAAATTTAGAAGACTTAAAAGA
GCTGGGCAAAGAAATGGAACACATCTCAGAGAAAAATGACGAAGAAAAAGTTAATCAATCGCATGATACATCAAAGTCTT
CAAATTCATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9145.71 Da        Isoelectric Point: 9.7603

>AT178955 WP_194450193.1 NZ_CP063849:213441-213698 [Paludibaculum fermentans]
MYTTHLRKVGGSIMLAVPPALLDLLGLRPGVKVGLAVEGGQLVVKPHSRPRYTLDELLAQCDAKAVRSQEDREWARGKAA
GGELI

Download         Length: 258 bp

>AT178955 NZ_CP084434:c573311-572712 [Staphylococcus lugdunensis]
ATGGCAATGAACTTTAAAGTATTTGAAAATAAAGATCAAGTTGCAGAGTATTCAGCAGATATCATTAGAAAACAATTTAA
CAATAATCCTACTACAATTGCTGGATTTCATTTAAACAAAGAGGCATCACCAGTACTTGATATGCTTAAAAAGAATGTTG
ACCAACATGCGGTTGACTTCAGCCAAATTAACATTCTTGACTATGATCAAAATCAAGAATATTTCAAAGCGCTGGGGGTT
CCTGAGAGTCAAATTTATCCTATCTCATACGATCAAGATGCTGAAGCGTTTATCTCTGATAAAATCAAAACAAAAGATAA
TAAAGGGAAACTAATATTACAAGTAGCTTCAATTGATGATCAAGGAAACCTTAATATCAGTCTACGTCAAGGATTGTTAA
ATGCTAGAGAAATTATCTTAGTCATTACAGGACATAATAAAAAAGAAGTAGTAGAAAAACTGTATAATGAAAATGGAAAA
TCTAATTTTGAACCTGCTGATTTAAAAGCACATCGTATGGTAACGGTTATTTTAGACGAAGCGGCAGCTGAAGGTTTGCC
AGAAGATGTACGTCATTACTTTACTGATCGGTTTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References