Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 4458681..4459493 Replicon chromosome
Accession NZ_CP063845
Organism Gloeobacter morelensis MG652769

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag ISF26_RS21395 Protein ID WP_230841325.1
Coordinates 4458681..4459178 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag ISF26_RS21400 Protein ID WP_230841326.1
Coordinates 4459206..4459493 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISF26_RS21375 (ISF26_21325) 4453687..4454805 + 1119 WP_230841321.1 HlyD family efflux transporter periplasmic adaptor subunit -
ISF26_RS21380 (ISF26_21330) 4454798..4455958 + 1161 WP_230841322.1 ABC transporter permease DevC -
ISF26_RS21385 (ISF26_21335) 4455970..4456620 + 651 WP_230841323.1 TetR family transcriptional regulator -
ISF26_RS21390 (ISF26_21340) 4456817..4458484 - 1668 WP_230841324.1 FAD-dependent oxidoreductase -
ISF26_RS21395 (ISF26_21345) 4458681..4459178 - 498 WP_230841325.1 GNAT family N-acetyltransferase Toxin
ISF26_RS21400 (ISF26_21350) 4459206..4459493 - 288 WP_230841326.1 DUF1778 domain-containing protein Antitoxin
ISF26_RS21405 (ISF26_21355) 4459833..4460678 + 846 WP_230841327.1 Rpn family recombination-promoting nuclease/putative transposase -
ISF26_RS21410 (ISF26_21360) 4460846..4464433 + 3588 WP_230841328.1 methionine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(40-145)

Antitoxin

Vibrio phage ICP1, Orf50

(15-89)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18139.22 Da        Isoelectric Point: 9.8392

>T178954 WP_230841325.1 NZ_CP063845:c4459178-4458681 [Gloeobacter morelensis MG652769]
VNQSKPSAPQLLAAHHRLEEFDCAEPQLNTWLKQHAMRNHEAGASRTFVVCRENRILAYYCLAMGAVSLSIAPGKVRRNM
PDPIPVAVIGRLAVDRKLEGQGYGKGLVKDAVLRVIQVSEVIGVRAILVHTISERAGDFYLRRGFLAAPVEPLTLMLPMK
DAAGF

Download         Length: 498 bp

>T178954 NZ_CP084433:c3259011-3258643 [Edwardsiella piscicida]
ATGTTTCTGCTGGGGCACGGCGCGCTGGTACTGGCGATCCTGCTGGCGCCCTGGCCGGAAAACTACAGCGTATTCTGGCT
GATTCTGCTGGTGGCGGTGATCTTTGAGTGTATCCGCAGCCAGCGCCGGATTGCGCGTAACCGCGGTGAGCTGCAGCTGC
TGGCGCCGCAGGTGTGGCACTGGCAGCTGCGCGAGTGGCGCCTGGCCCGACGCCCTTGGGTTAGCGATCTGGGGGCGCTG
CTGATCCTGCAGAGTACCCATGGTGCGCCGTGCCGCCGCCGTCTGTGGCTGGCGGCCGACAGCATGAGCCGCGAAGAGTG
GGGGCAGCTGCGCCGCACGCTGCTCGATGCGGGCGACGATCGCGCATAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10538.08 Da        Isoelectric Point: 5.1053

>AT178954 WP_230841326.1 NZ_CP063845:c4459493-4459206 [Gloeobacter morelensis MG652769]
MAIADRPTPSKDIVINLRAKQSQRELIDQAAAALGKSRSDFMIESSLRAAETVLLERLFFHLDEAAYAQFIAALEGPPQL
NERLLTTLSAKAPWE

Download         Length: 288 bp

>AT178954 NZ_CP084433:c3259306-3259040 [Edwardsiella piscicida]
ATGGATATCAATAATAAAGCGCGGGTTCACTGGGCGTGCCGCCGCGGAATGCGCGAGCTGGATATCGCCATCATGCCTTT
CTTTGAACATGAGTATGATGCGCTTAACGATGCCGATAAACAGACCTTTGTCCGCCTGCTGGCCTGTGACGATCCTGAGC
TATTTAAATGGCTGATGAACCAGGGTAAGCCGGATGACGCCGATCTGGCCCGCATGATTACGCTGATTCAGACGCGAAAT
AAAGAACGTGGTCCTTTGGCGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References