Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 4445189..4445844 Replicon chromosome
Accession NZ_CP063845
Organism Gloeobacter morelensis MG652769

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ISF26_RS21335 Protein ID WP_230844266.1
Coordinates 4445416..4445844 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ISF26_RS21330 Protein ID WP_230841314.1
Coordinates 4445189..4445416 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISF26_RS21300 (ISF26_21250) 4441019..4441264 + 246 WP_230841309.1 hypothetical protein -
ISF26_RS21305 (ISF26_21255) 4441347..4441715 + 369 WP_230844265.1 P-II family nitrogen regulator -
ISF26_RS21310 (ISF26_21260) 4441751..4443322 + 1572 WP_230841310.1 bifunctional aminoglycoside phosphotransferase/ATP-binding protein -
ISF26_RS21315 (ISF26_21265) 4443367..4443921 + 555 WP_230841311.1 universal stress protein -
ISF26_RS21320 (ISF26_21270) 4443869..4444159 - 291 WP_230841312.1 BolA/IbaG family iron-sulfur metabolism protein -
ISF26_RS21325 (ISF26_21275) 4444528..4444839 + 312 WP_230841313.1 hypothetical protein -
ISF26_RS21330 (ISF26_21280) 4445189..4445416 + 228 WP_230841314.1 antitoxin Antitoxin
ISF26_RS21335 (ISF26_21285) 4445416..4445844 + 429 WP_230844266.1 hypothetical protein Toxin
ISF26_RS21340 (ISF26_21290) 4445925..4447481 - 1557 WP_230841315.1 NAD(P)/FAD-dependent oxidoreductase -
ISF26_RS21345 (ISF26_21295) 4447651..4450221 - 2571 WP_230841316.1 glycogen/starch/alpha-glucan phosphorylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15490.83 Da        Isoelectric Point: 7.3001

>T178953 WP_230844266.1 NZ_CP063845:4445416-4445844 [Gloeobacter morelensis MG652769]
MTYLLDVNVLLSLSDPMHVHHEAAHRWFAARGRSAWATCPITENGFIRIASHPGYPNRPGDVPVVMGILRQFCAAQGHHF
WGANVSLLSMLHTGIVLTHSQITDIFLLGLAAHQGGKLATFDRRIAVDTVHGGNEALELIAP

Download         Length: 429 bp

>T178953 NZ_CP084433:1769672-1769773 [Edwardsiella piscicida]
GCAAGGCACTCAATGCCTGCATAATGCCAACTTTTAGCGCACGGCTCTCCAAAAGAGCCATTCCCCTAGACCTGACACAG
GAATCGTGTTAGGTCTTTTTTT

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8186.34 Da        Isoelectric Point: 5.0022

>AT178953 WP_230841314.1 NZ_CP063845:4445189-4445416 [Gloeobacter morelensis MG652769]
MRTTLDLEEDVLLAAKEIARQRGVSLGKVFSDLARQALSGSSDVSIRNGVPLFPVHDQSGIATLELINRLRDEVP

Download         Length: 228 bp

>AT178953 NZ_CP084433:c1769775-1769665 [Edwardsiella piscicida]
ATAAAAAAAGACCTAACACGATTCCTGTGTCAGGTCTAGGGGAATGGCTCTTTTGGAGAGCCGTGCGCTAAAAGTTGGCA
TTATGCAGGCATTGAGTGCCTTGCTCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References