Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3884629..3885302 Replicon chromosome
Accession NZ_CP063845
Organism Gloeobacter morelensis MG652769

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ISF26_RS18595 Protein ID WP_230840810.1
Coordinates 3884874..3885302 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ISF26_RS18590 Protein ID WP_230840809.1
Coordinates 3884629..3884877 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISF26_RS24765 3880254..3880388 - 135 WP_256997506.1 hypothetical protein -
ISF26_RS18575 (ISF26_18515) 3880444..3882321 + 1878 WP_230840807.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -
ISF26_RS18580 (ISF26_18520) 3882650..3882982 + 333 WP_011140882.1 thioredoxin -
ISF26_RS18585 (ISF26_18525) 3882995..3884518 + 1524 WP_230840808.1 pyruvate carboxylase subunit B -
ISF26_RS18590 (ISF26_18530) 3884629..3884877 + 249 WP_230840809.1 hypothetical protein Antitoxin
ISF26_RS18595 (ISF26_18535) 3884874..3885302 + 429 WP_230840810.1 type II toxin-antitoxin system VapC family toxin Toxin
ISF26_RS18600 (ISF26_18540) 3885395..3886558 + 1164 WP_230840811.1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain -
ISF26_RS18605 (ISF26_18545) 3886688..3886975 - 288 WP_230840812.1 metalloregulator ArsR/SmtB family transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-133)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15903.39 Da        Isoelectric Point: 6.9676

>T178952 WP_230840810.1 NZ_CP063845:3884874-3885302 [Gloeobacter morelensis MG652769]
MILVDTNLLVYAHIRSFPQHQEARAWLDEKLNEPIPVGLPWPSLLGFARLVTNPRIFGQPLSTQATWRQIESWLGCPSVW
IPQPTARHREVLASLLISAAVQANLVPDAHLAALAIEHGLLLCSTDGDFARFSGLRWENPLR

Download         Length: 429 bp

>T178952 NZ_CP084433:c1748588-1748307 [Edwardsiella piscicida]
ATGACCTATAAACTGAGCTTTGAAAAGCGAGCCCTGAAAGAGTGGAAAAAACTGGCACCGCCCATTCAAAGCCAGTTGAA
AAAGAAACTGATCGAACGCCTGGAAAATCCACATATCCCGGCCGCCCGCTTAAGTGGGCGCGCTAACCGTTATAAAATAA
AATTACGATCTTCCGGTTATCGGTTAGTTTATGAAGTCAACGATAGCGAAATCATCCTGCTGGTGATCGCTATCGGTAAA
CGAGCCGATAACGACGTGTACCTAGCGGCAGACGGTCGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8956.33 Da        Isoelectric Point: 8.6607

>AT178952 WP_230840809.1 NZ_CP063845:3884629-3884877 [Gloeobacter morelensis MG652769]
MRTTLSLDDDVSVQLVRLQKTTGKSFKQVVNDALRLGLQQMSAPTLPRRPYSTPTVDLGPSLIGSLDKVSEVLAIVEGEA
FR

Download         Length: 249 bp

>AT178952 NZ_CP084433:c1748829-1748578 [Edwardsiella piscicida]
ATGGCATACCAAATTCTCACTACAACAGCCGCCAGTATTACCGATCTAAAACGCAATCCGATGGGTACCATTGCTGAGGG
TGACGGTAATGCCGTCGCAATCTTAAACCGGAATGAGCCGGCCTTTTACTGCGTTCCACCGGAGCTCTATGCTTACTACC
TGGAGCTGGCTGAAAATGCTGCTCTTAATCGTATCGCCGATGAGCGTCTAGAGGACGCTGAATTCGTCAGCGTAAATATC
GATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References