178951

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3006772..3007442 Replicon chromosome
Accession NZ_CP063845
Organism Gloeobacter morelensis MG652769

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ISF26_RS14395 Protein ID WP_256997493.1
Coordinates 3007011..3007442 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ISF26_RS14390 Protein ID WP_230839987.1
Coordinates 3006772..3007014 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISF26_RS14370 (ISF26_14300) 3002495..3003574 - 1080 WP_230839983.1 isocitrate/isopropylmalate dehydrogenase family protein -
ISF26_RS14375 (ISF26_14305) 3003706..3004845 + 1140 WP_230839984.1 tocopherol cyclase family protein -
ISF26_RS14380 (ISF26_14310) 3004857..3005702 + 846 WP_230839985.1 methyltransferase domain-containing protein -
ISF26_RS14385 (ISF26_14315) 3005702..3006736 + 1035 WP_230839986.1 VOC family protein -
ISF26_RS14390 (ISF26_14320) 3006772..3007014 + 243 WP_230839987.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ISF26_RS14395 (ISF26_14325) 3007011..3007442 + 432 WP_256997493.1 type II toxin-antitoxin system VapC family toxin Toxin
ISF26_RS14400 (ISF26_14330) 3007454..3007816 - 363 WP_230839989.1 hypothetical protein -
ISF26_RS14405 (ISF26_14335) 3007892..3008194 - 303 WP_230839990.1 serine hydrolase -
ISF26_RS14410 (ISF26_14340) 3008191..3009261 - 1071 WP_230839991.1 dipeptide epimerase -
ISF26_RS14415 (ISF26_14345) 3009258..3010328 - 1071 WP_230839992.1 DUF1611 domain-containing protein -
ISF26_RS14420 (ISF26_14350) 3010351..3011292 - 942 WP_230839993.1 ornithine carbamoyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-129)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-59)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15306.66 Da        Isoelectric Point: 6.8708

>T178951 WP_256997493.1 NZ_CP063845:3007011-3007442 [Gloeobacter morelensis MG652769]
VRLLLDTCVIAELRKPRPEPTVVDTIGAVADDNLYLSVLTVGEIFKGIGLLPPGTKKQELNHWLLGLQVQFAERILAVDA
ETAEIWGKGVAAATQAGVTVPTIDSLIAATAARHGLAVATRNVRHFHRFGVSVVNPWDGQNAP

Download         Length: 432 bp

>T178951 NZ_CP084433:c1734420-1734091 [Edwardsiella piscicida]
ATGAACTACACTATTGAGTACTACAGCGAAGAGGTTCGGCTTGAGGTCGATCAGTTGCCAATGGGTATGCGGGTTCGATA
CCAGCATCTCGTTGAACGCATGGAAATCTACGGTAGTAATCTCGGAGAACCACACACAAGCCCTTTTGGCGATGGGCTTT
TTGAGCTTCGAATCAAAGGCAGTGATGGCATCGCCCGCGTGTTTTACTGCACTCTTACTGGAAAACGTATCGTCATGCTG
CACAGCTTCATCAAGAAAACCCAGAAGACGCCAAGCGCTGAACGTAAGAAGGCTGAAACCAGAATGAAGGAGGTAAAACA
TGGCTGGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9057.23 Da        Isoelectric Point: 5.1369

>AT178951 WP_230839987.1 NZ_CP063845:3006772-3007014 [Gloeobacter morelensis MG652769]
MQWQLADAKNRFSDLVERALREGPQTVTKRGIEAVVVLSAEEYRRLSGAKPSFKAYLMQGPSFEGLDLERDQSAERSVEL

Download         Length: 243 bp

>AT178951 NZ_CP084433:c1734101-1733793 [Edwardsiella piscicida]
ATGGCTGGTAAACGCACCCCCCCCACGATGACGCATGATGAAATGGCTGCAAAATGGATGGAAGACCCGGCATTTAAAGC
AGAATACGATGCCATCGAAGAGGAATACGCCCTACTCGATGAAATGCTCGCAGCCCGCAAAAACGCGGGGCTGACCCAGG
CGCAGGTCGCCGAACGTATGGGAACCAAGGCTACAGCGATCACTCGCATGGAAAGTAATTTAGCCTCCGGCCAAAGCGGG
CCATCATTCGCCACGCTGAAAAAATTTGCACACGCGACCGGCAAGAAACTGCAGATCCGGTTTGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References